Howard Frazer and his brother Frank take different paths to achieve their goals. Howard enlists in the U.S. Army, and qualifies as a combat medic. He is wounded in an Iraqi ambush.
Frank hopes for financial success, and manages to afford college. He finds a good position, but an episode of drunken driving causes the death of a little girl, and lands him in prison.
Howard meets Cathy, his high school girlfriend, who confesses to having a sexual episode with Frank. Howard feels anger and disgust at these revelations, and vows never to see his brother again. His wounds end his career as a combat medic.
News of the Ebola Pandemic raging in Africa presents another opportunity for him to be a medic. Howard flies to Liberia where he and Rory Donnelly, an Australian medic, confront the horrors of the disease for a year. Howard contracts Ebola, and nearly dies. When he recovers, he accepts Rory's offer to return with him to Australia. Howard falls in love with Ellen, Rory's sister, and they marry.
Frank regains his former position and marries only to lose his wife and baby in childbirth. The brothers have not spoken in years until a phone call from Ellen informs Frank that Howard is gravely ill...
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