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This book presents solutions to missing data problems through explicit or noniterative sampling calculation of Bayesian posteriors, based on the inver...Lees meer
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This text describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinical trials as well as the practical aspe...Lees meer
Quantitative Methodologies and Process for Safety Monitoring and Ongoing Benefit Risk Evaluation provides a comprehensive coverage on safety monitorin...Lees meer
This text describes the core scientific concepts of designing, data monitoring, analyzing, and reporting clinical trials as well as the practical aspe...Lees meer
Like the well-regarded and bestselling second edition, Sample Size Calculations in Clinical Research, Third Edition , presents statistical procedures ...Lees meer
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This text gives graduate students with diverse backgrounds across the health, medical, social, and mathematical sciences a solid, unified foundation i...Lees meer
Drug development sponsors cannot run individual trials for all products in all indications. This results in missed opportunities. Clinical trial progr...Lees meer
This book concentrates on the biostatistics component of clinical trials. This new, second edition is updated throughout and includes three new chapte...Lees meer
A disease is defined as rare if the prevalence is fewer than 200,000 in the United States. It is estimated that there are more than 7,000 rare disease...Lees meer
This book covers classic epidemiological designs that use a reference/control group, including case-control, case-cohort, nested case-control and vari...Lees meer
As the development of medicines has become more globalized, the geographic variations in the efficacy and safety of pharmaceutical products need to be...Lees meer
Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages ...Lees meer
This book presents a wide variety of statistical approaches for analyzing pharmacoepidemiologic data. It covers both commonly used techniques, such as...Lees meer
This book shows how model-assisted designs can greatly improve the efficiency and simplify the conduct of early-phase dose finding and optimization tr...Lees meer
Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Fourth Edition focuses on the statistical aspects ofmedicine with a medical...Lees meer
Longitudinal studies often investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest. An example ...Lees meer
With ever-rising healthcare costs, evidence generation through Health Economics and Outcomes Research (HEOR) plays an increasingly important role in d...Lees meer
With ever-rising healthcare costs, evidence generation through Health Economics and Outcomes Research (HEOR) plays an increasingly important role in d...Lees meer
Methodologies for Biosimilar Product Development covers the practical and challenging issues that are commonly encountered during the development, rev...Lees meer
Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare covers exciting developments at the intersection of computer science ...Lees meer