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Andrew Duncan's 'Observations on the Operation and Use of Mercury in the Venereal Disease' is a groundbreaking medical text that delves into the controversial topic of using mercury as a treatment for venereal diseases during the 18th century. Duncan's meticulous observations and detailed account of the effects of mercury on patients provide valuable insights into the medical practices of the time. His writing style is clear and concise, making the complex subject matter accessible to readers interested in the history of medicine. The book also serves as a reflection of the evolving scientific knowledge and ethical considerations surrounding medical treatments in the Enlightenment era. This text is a must-read for anyone interested in the history of medicine and the development of medical ethics. Andrew Duncan, a prominent Scottish physician and professor of medicine, was influenced by his experiences in treating patients with venereal diseases. His dedication to advancing medical knowledge and improving patient care is evident in this seminal work. Duncan's expertise and passion for medicine shine through in his thorough analysis of the use of mercury, making this book a valuable contribution to the field of medical history.