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The book covers all X-ray modalities, including CT, mammography, fluoroscopy, dental radiography, and fusion imaging like PET-CT and SPECT-CT. It simplifies complex concepts for beginners while offering depth for advanced learners. Each chapter is engaging and addresses common questions from students and professionals. The book begins with radiation science basics, starting with "What is radiation?" and expanding through seven subsections to build a solid foundation. The chapter on X-ray tubes introduces essential concepts for understanding other modalities. Subsequent chapters explore the physics, operational principles, quality control, and safety of each modality. The fusion imaging section provides detailed insights into PET-CT and SPECT-CT quality assurance, enabling readers to perform these procedures independently. Radiation safety topics include specific guidance for female patients, female radiation workers, and faetal exposure. Chapters on paediatric care and global radiology department planning offer practical insights. Each chapter concludes with multiple-choice, short-answer, and long-answer questions to reinforce learning and aid exam preparation. Written in clear, accessible language, the book integrates hardware, quality control, and clinical applications into one volume, aligned with international curricula. This indispensable resource is ideal for radiography students, technologists, researchers and professionals seeking to enhance their knowledge and skills in medical imaging.